2. Signaling Pathways
  3. Cell Cycle/DNA Damage
  4. Polo-like Kinase (PLK)
  5. Polo-like Kinase (PLK) Degrader

Polo-like Kinase (PLK) Degrader

Polo-like Kinase (PLK) Isoform Comparison

Polo-like Kinase (PLK) Degraders (2):

Cat. No. Product Name Effect Purity
  • HY-157427
    PROTAC PLK1 Degrader-1
    		Degrader
    PROTAC PLK1 Degrader-1 (DD-2) is a potent PROTAC PLK1 degrader. PROTAC PLK1 Degrader-1 selectively induces PLK1 degradation in cancer cells, including HeLa (DC50=2.5 μM) and nonsmall cell lung cancer (NSCLC), through the N-degron pathway.
  • HY-149324
    SP27
    		Degrader 98.87%
    SP27 is a PROTAC that can selective degrades PLK4, with a DC50 of 19.5 nM. SP27 can be used for the research of breast cancer.